Sanofi and Regeneron Present Results from Pivotal Phase 3 Study of Sarilumab …

PARIS and TARRYTOWN, N.Y., Nov. 8, 2015 /PRNewswire/ -- Sanofi and Regeneron Pharmaceuticals, Inc. today announced results from a pivotal Phase 3 study of sarilumab, an investigational, human antibody against the IL-6 receptor. The results of the study, SARIL-RA-TARGET, are being presented today at an oral session during the American College of Rheumatology (ACR) Annual Meeting in San Francisco, California. The study Read more [...]

Don’t look down: Tech unicorns face reckoning as valuations detach from reality

Some pundits have even predicted that Dropbox will be the most high-profile victim of a new kind of dotcom bubble, in which the cheap and easy money that has inflated private valuations runs out, leaving start-ups scrambling to adjust to a new reality. In 1999, hundreds of tech firms flocked to the public markets, with a rush of investor enthusiasm valuing companies often without any real business model in the hundreds of millions of dollars. When confidence collapsed, so did share prices, with Read more [...]

Weekend events offer something for the entire family

The cast of Disney on Ice presents Let’s Celebrate poses for A Very Merry Unbirthday Party. The show comes to Greenville Nov. 25, but families can get free tickets Saturday by donating to charity.(Photo: Feld Entertainment)Whether you love family-friendly plays, music, or want to teach the kids how to give back to the community, there’s an event happening in the Upstate this weekend.Feeling up for a play this weekend? “Mary Poppins” will be presented by Greer Children’s Theatre Nov. 6-8, Read more [...]

Derry WII hangar listing ‘may hamper development’

Concerns have been raised that a proposal to list three Second World War aircraft hangars in Derry may hamper future development near the city’s airport. Sinn Fein Councillor Patricia Logue queried the implications of the suggested listings, which were among several in Derry recently announced by the Department for the Environment’s Historic Buildings Unit.The DoE has now asked for the council’s views on the listings, and a report brought before this week’s meeting of the council’s Read more [...]

The Coronet music venue in Elephant & Castle to close in January 2017

South London is to lose another famous music venue after the operators of The Coronet at Elephant Castle threw in the towel on their valiant attempts to save the venue from demolition. We first reported on a petition to save the music venue and former cinema in July 2014, but despite attracting over 4,600 signatures, the decision was made to flatten the Coronet as part of the major redevelopment of the Elephant Castle Shopping Centre site, in a multi-million scheme led by corporate property Read more [...]