Following a four-year review, the US Fish and Wildlife Service (USFWS) will remove the eastern cougar from its  list of endangered and threatened species — where it has been for the last 43 years.

The big cat, which once roamed North America from Canada to South Carolina, will no longer receive Endangered Species Act protections.

Cougars – along with their cousins panthers and pumas – were once the most widely distributed land mammal in the western hemisphere, but have been driven out from two-thirds of land that they once occupied, wildlife biologists have said.

There are still an estimated 30,000 mountain lions in the western United States, but the Florida panther is a highly endangered species — there are fewer than 100 left.

It’s thought that these two animals account for the vast majority of cougar sightings in the last 100 or so years.

The last confirmed sighting of an eastern cougar was one killed by a hunter Maine in 1938. Before that, one was seen in New Brunswick, Canada six years earlier.

The last Eastern Cougar was seen in 1938 (USFWS)

The cat – which was between 6 and 8 feet long and weighed between 105 to 140 pounds – was largely wiped out in the 19th century following the arrival of European immigrants who killed them to protect themselves and their livestock.

Their demise was also caused by deforesting in the region, which drove their prey – the white-tailed deer – to the brink of extinction as well.

Additional reporting by Reuters